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・ Neuropathic arthropathy
・ Neuropathic pain
・ Neuropathology
・ Neuropathology and Applied Neurobiology
・ Neuropathy (disambiguation)
・ Neuropathy target esterase
・ Neuropathy, ataxia, and retinitis pigmentosa
・ Neuropeptide
・ Neuropeptide B
・ Neuropeptide B/W receptor
・ Neuropeptide FF
・ Neuropeptide FF receptor
・ Neuropeptide FF receptor 1
・ Neuropeptide FF receptor 2
・ Neuropeptide receptor
Neuropeptide S
・ Neuropeptide S receptor
・ Neuropeptide VF precursor
・ Neuropeptide Y
・ Neuropeptide Y receptor
・ Neuropeptide Y receptor Y1
・ Neuropeptide Y receptor Y2
・ Neuropeptide Y receptor Y5
・ Neuropeptide Y receptor Y6
・ Neuropeptidergic
・ Neuropeptides B/W receptor 1
・ Neuropeptides B/W receptor 2
・ Neuroph
・ Neurophana
・ Neuropharmacology


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Neuropeptide S : ウィキペディア英語版
Neuropeptide S

Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas.〔 〕 NPS binds specifically to a newly de-orphaned G protein-coupled receptor, NPSR. Animal studies show that NPS suppresses anxiety and appetite, induces wakefulness and hyperactivity, including hyper-sexuality, and plays a significant role in the extinction of conditioned fear. It has also been shown to significantly enhance dopamine activity in the mesolimbic pathway.〔
== Synthetic ligands ==

The non-peptide NPS receptor antagonist SHA-68 blocks the effects of NPS in animals and is anxiogenic. Several peptide derived NPS agonists and antagonists have also been developed.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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